• Differentially Expressed MicroRNAs in Meningiomas Grades I and II Suggest Shared Biomarkers with Malignant Tumors 

      El-Gewely, Mohamed Raafat; Andreassen, Morten; Walquist, Mari; Ursvik, Anita; Knutsen, Erik; Nystad, Mona; Coucheron, Dag H; Myrmel, Kristin Smistad; Hennig, Rune; Johansen, Steinar D (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-03)
      Meningiomas represent the most common primary tumors of the central nervous system, but few microRNA (miRNA) profiling studies have been reported so far. Deep sequencing of small RNA libraries generated from two human meningioma biopsies WHO grades I (benign) and II (atypical) were compared to excess dura controls. Nineteen differentially expressed miRNAs were validated by RT-qPCR using tumor RNA ...
    • MicroRNAs as potential biomarkers in Merkel cell carcinoma 

      Konstantinell, Aelita Gloria Virginia; Coucheron, Dag H; Sveinbjørnsson, Baldur; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-26)
      Merkel cell carcinoma (MCC) is a rare and aggressive type of skin cancer associated with a poor prognosis. This carcinoma was named after its presumed cell of origin, the Merkel cell, which is a mechanoreceptor cell located in the basal epidermal layer of the skin. Merkel cell polyomavirus seems to be the major causal factor for MCC because approximately 80% of all MCCs are positive for viral DNAs. ...
    • MicroRNAs in Daphnia magna identified and characterized by deep sequencing, genome mapping and manual curation 

      Coucheron, Dag H; Wojewodzic, Marcin; Bøhn, Thomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-04)
      MicroRNAs (miRNAs) are small non-coding RNAs that function in RNA silencing and post-transcriptional regulation of gene expression in most organisms. The water flea, <i>Daphnia magna</i> is a key model to study phenotypic, physiological and genomic responses to environmental cues and miRNAs can potentially mediate these responses. By using deep sequencing, genome mapping and manual curations, we ...
    • Mitochondrial genome variation of Atlantic cod 

      Jørgensen, Tor Erik; Karlsen, Bård Ove; Emblem, Åse; Breines, Ragna; Andreassen, morten; Rounge, Trine Ballestad; Nederbragt, Alexander Johan; Jakobsen, Kjetill Sigurd; Nymark, Marianne; Ursvik, anita; Coucheron, Dag H; Jakt, Lars Martin; Nordeide, Jarle Tryti; Moum, Truls Borg; Johansen, Steinar Daae (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-19)
      Objective:<br> The objective of this study was to analyse intraspecifc sequence variation of Atlantic cod mitochondrial DNA, based on a comprehensive collection of completely sequenced mitochondrial genomes. <br>Results:<br> We determined the complete mitochondrial DNA sequence of 124 cod specimens from the eastern and western part of the species’ distribution range in the North Atlantic Ocean. ...